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1. (WO2017167636) BRAIN TISSUE STIMULATION METHOD, APPARATUS AND COMPUTER PROGRAM
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Pub. No.: WO/2017/167636 International Application No.: PCT/EP2017/056920
Publication Date: 05.10.2017 International Filing Date: 31.03.2017
IPC:
A61N 1/36 (2006.01) ,A61B 5/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
N
ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1
Electrotherapy; Circuits therefor
18
Applying electric currents by contact electrodes
32
alternating or intermittent currents
36
for stimulation, e.g. heart pace-makers
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
04
Measuring bioelectric signals of the body or parts thereof
Applicants: UNIVERSITE DE RENNES 1[FR/FR]; 2 rue du Thabor - CS 46510 35065 RENNES CEDEX, FR
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE[FR/FR]; 101, rue de Tolbiac 75013 PARIS 13, FR
Inventors: BENQUET, Pascal; FR
WENDLING, Fabrice; FR
MODOLO, Julien; FR
Agent: VIDON BREVETS & STRATÉGIE; 90333 B Technopôle Atalante 16B rue de Jouanet 35703 Rennes Cedex 7, FR
Priority Data:
16000751.431.03.2016EP
Title (EN) BRAIN TISSUE STIMULATION METHOD, APPARATUS AND COMPUTER PROGRAM
(FR) PROCÉDÉ, APPAREIL ET PROGRAMME INFORMATIQUE DE STIMULATION DE TISSU CÉRÉBRAL
Abstract:
(EN) The invention relates to a local stimulation method of a predetermined region of brain tissue, said brain tissue comprising at least GABAergic neuron type. According to the invention, said method comprises at least one activation step (10) of a set of bipolar electrodes (SBE), according to a predetermined electric intensity (PEI) and a predetermined biphasic pulse frequency (PBPF), delivering a predetermined electric field (PEF), said predetermined electric field (PEF) inducing an activation of said GABAergic type neurons and a virtual absence of activation of other types of neurons.
(FR) L'invention concerne un procédé de stimulation locale d'une région prédéfinie de tissu cérébral, ledit tissu cérébral comprenant au moins un type de neurones GABAergiques. Selon l'invention, ledit procédé comprend au moins une étape d'activation (10) d'un ensemble d'électrodes bipolaires (SBE), en fonction d'une intensité électrique prédéfinie (PEI) et d'une fréquence d'impulsion biphasique prédéfinie (PBPF), délivrant un champ électrique prédéfini (PEF), ledit champ électrique prédéfini (PEF) induisant une activation desdits neurones de type GABAergique et une absence virtuelle d'activation d'autres types de neurones.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)