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1. (WO2017161370) TREATMENT OF COGNITIVE AND MOOD SYMPTOMS IN NEURODEGENERATIVE AND NEUROPSYCHIATRIC DISORDERS WITH ALPHA5-CONTAINING GABAA RECEPTOR AGONISTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/161370 International Application No.: PCT/US2017/023206
Publication Date: 21.09.2017 International Filing Date: 20.03.2017
IPC:
A61K 31/5517 (2006.01) ,A61P 25/18 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
55
having seven-membered rings, e.g. azelastine, pentylenetetrazole
551
having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
5513
1,4-Benzodiazepines, e.g. diazepam
5517
condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
18
Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Applicants:
UWM RESEARCH FOUNDATION, INC. [US/US]; 1440 East North Avenue Milwaukee, WI 53202, US
CENTRE FOR ADDICTION AND MENTAL HEALTH [CA/CA]; 1001 Queen Street West Toronto, ON M6J 1H4, CA
UNIVERSITY OF BELGRADE - FACULTY OF PHARMACY [RS/RS]; Vojvode Stepe 450 Belgrade, 11221, RS
Inventors:
COOK, James M.; US
LI, Guanguan; US
POE, Michael, Ming-Jin; US
SAVIC, Miroslav M.; RS
SIBILLE, Etienne; CA
Agent:
YAGER, Charlene L.; US
Priority Data:
62/310,40918.03.2016US
Title (EN) TREATMENT OF COGNITIVE AND MOOD SYMPTOMS IN NEURODEGENERATIVE AND NEUROPSYCHIATRIC DISORDERS WITH ALPHA5-CONTAINING GABAA RECEPTOR AGONISTS
(FR) TRAITEMENT DES SYMPTÔMES COGNITIFS ET DES TROUBLES DE L'HUMEUR DANS DES TROUBLES NEURODÉGÉNÉRATIFS ET NEUROPSYCHIATRIQUES AVEC DES AGONISTES DU RÉCEPTEUR GABAA CONTENANT ALPHA5
Abstract:
(EN) Provided herein are alpha5-containing GABAA receptor agonists and pharmaceutical compositions and methods of treatment of cognitive and mood symptoms in neurodegenerative and neuropsychiatric disorders using them.
(FR) L'invention concerne des agonistes du récepteur GABAA contenant alpha5, des compositions pharmaceutiques utilisant ces agonistes, et des procédés de traitement des symptômes cognitifs et des troubles de l'humeur dans des troubles neurodégénératifs et neuropsychiatriques au moyen de ces agonistes.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2017235665CA3016491EP3439665