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|1. (WO2017157323) LIPOPOLYSACCHARIDE BINDING PROTEIN POLYPEPTIDE AND PHARMACEUTICAL USE THEREOF|
|Title:||LIPOPOLYSACCHARIDE BINDING PROTEIN POLYPEPTIDE AND PHARMACEUTICAL USE THEREOF|
Provided are a lipopolysaccharide (LPS) binding protein polypeptide and the pharmaceutical use thereof, wherein the amino acid sequence of the lipopolysaccharide binding protein polypeptide is DHGHKHKHGHGHGKH, and the lipopolysaccharide binding protein polypeptide is derived from a high molecular weight kininogen (HK) protein in human plasma itself. The lipopolysaccharide binding protein polypeptide is injected into a mouse through intraperitoneal injection, and can reduce the mortality of endotoxemia caused by LPS in mice and inhibit the production of inflammatory factors.