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1. (WO2017157173) PAPILLOMAVIRUS CHIMERIC PROTEIN AND APPLICATION THEREOF
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Pub. No.: WO/2017/157173 International Application No.: PCT/CN2017/075402
Publication Date: 21.09.2017 International Filing Date: 02.03.2017
IPC:
C12N 15/37 (2006.01) ,C12N 15/63 (2006.01) ,C12N 5/10 (2006.01) ,C07K 14/025 (2006.01) ,A61K 39/12 (2006.01) ,A61P 31/20 (2006.01)
[IPC code unknown for C12N 15/37][IPC code unknown for C12N 15/63][IPC code unknown for C12N 5/10][IPC code unknown for C07K 14/025][IPC code unknown for A61K 39/12][IPC code unknown for A61P 31/20]
Applicants:
中国医学科学院基础医学研究所 INSTITUTE OF BASIC MEDICAL SCIENCES, CHINESE ACADEMY OF MEDICAL SCIENCES [CN/CN]; 中国北京市 东城区东单三条5号 5 Dongdan San Tiao, Dongcheng District, Beijing 100005, CN
Inventors:
许雪梅 XU, Xuemei; CN
陈雪 CHEN, Xue; CN
张婷 ZHANG, Ting; CN
王志荣 WANG, Zhirong; CN
刘洪洋 LIU, Hongyang; CN
望朔 WANG, Shuo; CN
胡美丽 HU, Meili; CN
Agent:
北京戈程知识产权代理有限公司 GE CHENG & CO.,LTD.; 中国北京市 东城区东长安街1号东方广场东三办公楼19层程伟 David W. Cheng Level 19,Tower E3, The Towers, Oriental Plaza, No.1,East Chang An Avenue, Dongcheng District Beijing 100738, CN
Priority Data:
201610146109.515.03.2016CN
Title (EN) PAPILLOMAVIRUS CHIMERIC PROTEIN AND APPLICATION THEREOF
(FR) PROTÉINE CHIMÈRE DE PAPILLOMAVIRUS ET SON APPLICATION
(ZH) 一种乳头瘤病毒嵌合蛋白及其用途
Abstract:
(EN) Provided is a papillomavirus chimeric protein, the skeleton thereof being a papillomavirus L1 protein or a mutant thereof, at least one human papillomavirus 33-type L2 protein or mutant polypeptide thereof being embedded on the skeleton. The present papillomavirus chimeric protein can be used for preparing a vaccine for preventing papillomavirus infections and infection induced diseases.
(FR) La présente invention concerne une protéine chimère de papillomavirus, dont le squelette est une protéine L1 de papillomavirus ou un mutant de celle-ci, au moins une protéine L2 de papillomavirus humain de type 33 ou un polypeptide muté de celle-ci étant intégré(e) dans le squelette. La protéine chimère de papillomavirus selon l'invention peut être utilisée pour préparer un vaccin destiné à prévenir les infections à papillomavirus et les maladies induites par ces infections.
(ZH) 提供了一种乳头瘤病毒嵌合蛋白,其骨架是乳头瘤病毒的L1蛋白或其突变体,所述的骨架上嵌合至少一个来自人乳头瘤病毒33型L2蛋白或其突变体多肽。该乳头瘤病毒嵌合蛋白可用于制备预防乳头瘤病毒感染及感染诱发的疾病的疫苗。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)