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1. (WO2017157063) NANOCARRIER-DRUG COMPOSITE FOR TREATING CANCER AND MANUFACTURING METHOD THEREOF
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Pub. No.: WO/2017/157063 International Application No.: PCT/CN2016/109823
Publication Date: 21.09.2017 International Filing Date: 14.12.2016
IPC:
A61K 47/42 (2017.01) ,A61K 47/04 (2006.01) ,A61K 47/02 (2006.01) ,A61K 45/00 (2006.01) ,A61K 49/08 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
42
Proteins; Polypeptides; Degradation products thereof; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
02
Inorganic compounds
04
Non-metals; Compounds thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
02
Inorganic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
06
Nuclear magnetic resonance (NMR) contrast preparations; Magnetic resonance imaging (MRI) contrast preparations
08
characterised by the carrier
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
深圳大学 SHENZHEN UNIVERSITY [CN/CN]; 中国广东省深圳市 南山区南海大道3688号 Nanhai Ave. 3688, Nanshan Shenzhen, Guangdong 518000, CN
Inventors:
杨海朋 YANG, Haipeng; CN
陈雪妮 CHEN, Xueni; CN
杨纬东 YANG, Weidong; CN
周润达 ZHOU, Runda; CN
戈早川 GE, Zaochuan; CN
Agent:
深圳市恒申知识产权事务所(普通合伙) HENSEN INTELLECTUAL PROPERTY FIRM; 中国广东省深圳市 福田区南园路68号上步大厦10H 10H Shangbu Building No.68 Nanyuan Road, Futian Shenzhen, Guangdong 518000, CN
Priority Data:
201610149183.216.03.2016CN
Title (EN) NANOCARRIER-DRUG COMPOSITE FOR TREATING CANCER AND MANUFACTURING METHOD THEREOF
(FR) COMPOSITE NANOPORTEUR-MÉDICAMENT POUR LE TRAITEMENT DU CANCER ET PROCÉDÉ POUR LE FABRIQUER
(ZH) 一种用于治疗癌症的复合纳米载药材料及其制备方法
Abstract:
(EN) Provided are a nanocarrier-drug composite for treating cancer and a manufacturing method thereof, the nanocarrier-drug composite comprising UCNPs functioning as a core, a layer of porous material coated on the surface of the core having an anti-cancer drug loaded in the pores, and a layer of a basic manganese compound deposited on the surface of the porous material. The surface of the basic manganese compound is labeled with one or more capture molecules or recognition molecules.
(FR) L'invention concerne un composite nanoporteur-médicament pour le traitement du cancer et un procédé pour le fabriquer, le composite nanoporteur-médicament comprenant des nanoparticules de conversion ascendante de photons (UCNP) en tant que noyau, une couche de matériau poreux appliquée sur la surface du noyau ayant un médicament anticancéreux étant chargé dans ses pores, et une couche d'un composé de manganèse basique déposée sur la surface du matériau poreux. La surface du composé de manganèse basique est marquée avec une ou plusieurs molécules de capture ou molécules de reconnaissance.
(ZH) 一种用于治疗癌症的复合纳米载药材料及其制备方法,其中,所述复合纳米载药材料以UCNPs为核,核表面覆盖一层多孔材料,孔内负载抗癌药物,多孔材料表面沉积一层碱性锰化合物,碱性锰化合物表面标记一种或多种捕获分子或识别分子。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)