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1. (WO2017156720) GLUCOCORTICOID COMBINED WITH POLYETHYLENE GLYCOL-MODIFIED INTERLEUKIN-2 FOR TREATING RESPIRATORY DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2017/156720 International Application No.: PCT/CN2016/076441
Publication Date: 21.09.2017 International Filing Date: 16.03.2016
Chapter 2 Demand Filed: 23.10.2017
IPC:
A61K 38/20 (2006.01) ,A61K 31/573 (2006.01) ,A61K 38/22 (2006.01) ,A61K 9/72 (2006.01) ,A61P 11/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
20
Interleukins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57
substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573
substituted in position 21, e.g. cortisone, dexamethasone, prednisone
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
72
for smoking or inhaling
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
Applicants:
谢彦晖 XIE, Yanhui [CN/CN]; CN
Inventors:
谢彦晖 XIE, Yanhui; CN
吴可菲 WU, Kefei; CN
马洁娴 MA, Jiexian; CN
Agent:
北京永新同创知识产权代理有限公司 NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD.; 中国北京市 东城区北三环东路36号北京环球贸易中心C座10层 10th Floor, Tower C, Beijing Global Trade Center, 36 North Third Ring Road East, Dongcheng District Beijing 100013, CN
Priority Data:
Title (EN) GLUCOCORTICOID COMBINED WITH POLYETHYLENE GLYCOL-MODIFIED INTERLEUKIN-2 FOR TREATING RESPIRATORY DISEASE
(FR) GLUCOCORTICOÏDE COMBINÉ À L'INTERLEUKINE-2 MODIFIÉE PAR POLYÉTHYLÈNE GLYCOL POUR TRAITER UNE MALADIE RESPIRATOIRE
(ZH) 糖皮质激素联合聚乙二醇修饰的白介素2治疗呼吸道疾病
Abstract:
(EN) The present invention provides a inhalable pharmaceutical composition comprising a glucocorticoid and a polyethylene glycol (PEG)-modified interleukin-2 for treating a respiratory disease. The invention further provides an application of a PEG-modified interleukin-2 for preparing a pharmaceutical composition for enhancing the efficacy of a glucocorticoid in treating the respiratory disease. The invention also provides a method for treating the respiratory disease.
(FR) La présente invention concerne une composition pharmaceutique pouvant être inhalée qui comporte un glucocorticoïde et une interleukine-2 modifiée par polyéthylène glycol (PEG) pour traiter une maladie respiratoire. L'invention concerne en outre une application d'une interleukine-2 modifiée par PEG pour préparer une composition pharmaceutique qui permet d'améliorer l'efficacité d'un glucocorticoïde pour traiter la maladie respiratoire. L'invention concerne également un procédé pour traiter la maladie respiratoire.
(ZH) 本发明提供了糖皮质激素与聚乙二醇(PEG)修饰的白介素2的吸入式药物组合物,用于呼吸道疾病治疗。本发明还提供了聚乙二醇修饰的白介素2在制备增强糖皮质激素对呼吸道疾病的疗效的药物组合物中的应用,以及治疗呼吸道疾病的方法。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)