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1. (WO2017156630) CONJUGATES ENHANCING TOTAL CELLULAR ACCUMULATION

Pub. No.:    WO/2017/156630    International Application No.:    PCT/CA2017/050337
Publication Date: Fri Sep 22 01:59:59 CEST 2017 International Filing Date: Thu Mar 16 00:59:59 CET 2017
IPC: C07K 19/00
A61K 47/66
A61K 51/08
C07H 21/00
C07K 14/025
C07K 16/00
C07K 16/28
C07K 7/08
C12N 15/113
G01N 33/574
Applicants: SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUEE SOCPRA SCIENCES SANTE ET HUMAINES, S.E.C.
Inventors: BEAUDOIN, Simon
LEYTON, Jeffrey Victor
Title: CONJUGATES ENHANCING TOTAL CELLULAR ACCUMULATION
Abstract:
The present description relates to a conjugated compound comprising cholic acid (ChAc) or a variant thereof, the ChAc conjugated to a non-cell penetrating peptide comprising a nuclear localization sequence (NLS) conjugated to a compound of interest.