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1. (WO2017156505) SINGLE DOSE NON-ADJUVANTED CUTANEOUS TETANUS VACCINE AND USES THEREOF

Pub. No.:    WO/2017/156505    International Application No.:    PCT/US2017/021979
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Sat Mar 11 00:59:59 CET 2017
IPC: A61K 39/08
A61K 9/00
Applicants: SPOROS THERAPEUTICS LLC
Inventors: SKOUNTZOU, Ioanna
SETH, Shaguna
ESSER, Stein, E.
COMPANS, Richard W.
Title: SINGLE DOSE NON-ADJUVANTED CUTANEOUS TETANUS VACCINE AND USES THEREOF
Abstract:
A vaccine composition and microneedle patch containing non-adjuvanted tetanus toxoid monobulk that is substantially concentrated. The composition and patch are useful in methods for preventing or treating tetanus infection in a subject, by administering a non-adjuvanted tetanus toxoid vaccine to the skin. The vaccine can be delivered by intradermal injection or microneedle patch and does not require cold storage.