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1. (WO2017156479) ROR1 CHIMERIC ANTIGEN RECEPTORS
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Pub. No.: WO/2017/156479 International Application No.: PCT/US2017/021945
Publication Date: 14.09.2017 International Filing Date: 10.03.2017
IPC:
A61K 39/395 (2006.01) ,C07K 14/47 (2006.01) ,C07K 16/18 (2006.01) ,C07K 14/705 (2006.01) ,C12N 15/09 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
Applicants:
BLUEBIRD BIO, INC. [US/US]; 60 Binney Street Cambridge, MA 02142, US
Inventors:
HINZ, Dominik; CZ
TRAD, Ahmad; CZ
MOLKENTHIN, Vera; DE
MORGAN, Richard; US
FRIEDMAN, Kevin; US
Agent:
MASHRUWALA, Mary Anne; US
LAHERTY, Carol; US
CHRISTIANSEN, William T.; US
ROGEL, Mark E.; US
FULLER, Alyson C.; US
NUDELMAN, Aaron S.; US
NGUYEN, Thu; US
GARELICK, Michael G.; US
TEAGUE, Lawrence; US
PHELAN, Jordan D.; US
Priority Data:
62/307,22711.03.2016US
62/307,23711.03.2016US
Title (EN) ROR1 CHIMERIC ANTIGEN RECEPTORS
(FR) RÉCEPTEURS ANTIGÉNIQUES CHIMÉRIQUES ANTI-ROR1
Abstract:
(EN) The invention provides improved compositions for adoptive cell therapies for cancers that express ROR1.
(FR) L'invention concerne des compositions améliorées pour des thérapies cellulaires adoptives de cancers exprimant ROR1.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)