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1. (WO2017156461) ANTIGEN-BINDING FUSION PROTEINS WITH MODIFIED HSP70 DOMAINS

Pub. No.:    WO/2017/156461    International Application No.:    PCT/US2017/021911
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Sat Mar 11 00:59:59 CET 2017
IPC: A61K 39/04
A61K 39/12
A61K 39/395
C12N 1/21
C12N 15/09
C12N 15/63
C12N 15/70
C07K 16/28
C07K 14/35
Applicants: APERISYS, INC.
THE GENERAL HOSPITAL CORPORATION
Inventors: BRAUNS, Timothy
POZNANSKY, Mark, C.
GELFAND, Jeffrey, A.
CHEN, Huabiao
MCCORMACK, Stephen, J.
Title: ANTIGEN-BINDING FUSION PROTEINS WITH MODIFIED HSP70 DOMAINS
Abstract:
The invention relates to fusion proteins comprising an antigen binding domain fused with a modified heat shock 70 protein. The invention further relates to methods of using the fusion proteins to induce an immune response to antigens and to treat diseases associated with antigens.