Search International and National Patent Collections

1. (WO2017156418) CATIONIC STEROIDAL ANTIBIOTIC COMPOSITIONS FOR THE TREATMENT OF DERMAL TISSUE

Pub. No.:    WO/2017/156418    International Application No.:    PCT/US2017/021832
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Sat Mar 11 00:59:59 CET 2017
IPC: A61K 31/575
C07J 41/00
A61P 31/00
Applicants: BRIGHAM YOUNG UNIVERSITY
Inventors: SAVAGE, Paul B.
GENBERG, Carl
BRACKEN, Ronald
Title: CATIONIC STEROIDAL ANTIBIOTIC COMPOSITIONS FOR THE TREATMENT OF DERMAL TISSUE
Abstract:
This disclosure relates to dermal treatment compositions, such as dermal fillers and tissue glues, and injectable compositions that incorporate one or more cationic steroidal antimicrobials (CSAs). The CSAs are incorporated into the dermal treatment compositions to provide effective antimicrobial, anti-inflammatory, analgesic, anti-swelling and/or tissue-healing properties. A treatment composition includes a component formed from a biologically compatible material suitable for injection into and/or application onto tissue at a treatment site. One or more CSA compounds are mixed with the biologically compatible material so that the one or more CSA compounds are incorporated within the composition, forming a reservoir of CSA compounds within the resulting bolus of the treatment composition after injection and/or application.