Search International and National Patent Collections

1. (WO2017156397) HETEROCYCLIC INHIBITORS OF PTPN11

Pub. No.:    WO/2017/156397    International Application No.:    PCT/US2017/021784
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Sat Mar 11 00:59:59 CET 2017
IPC: A61K 31/495
A61K 31/506
Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSYTEM
Inventors: CZAKO, Barbara
JONES, Philip
CROSS, Jason
LEONARD, Paul
Title: HETEROCYCLIC INHIBITORS OF PTPN11
Abstract:
The present invention relates to compounds which may be useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. The compounds are based on various substituted ring-fused pyrimidin-4-ones.