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1. (WO2017156148) FUNCTIONALIZED PRUSSIAN BLUE NANOPARTICES, COMBINATION PRUSSIAN BLUE NANOPARTICLE-BASED NANO-IMMUNOTHERAPHY AND APPLICATIONS THEREOF

Pub. No.:    WO/2017/156148    International Application No.:    PCT/US2017/021396
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Thu Mar 09 00:59:59 CET 2017
IPC: A61K 41/00
A61B 5/00
A61B 8/00
A61B 10/00
A61K 9/14
A61K 47/50
A61K 49/00
Applicants: CHILDREN'S NATIONAL MEDICAL CENTER
Inventors: FERNANDES, Rohan
SZE, Raymond, W.
CRUZ, Conrad, Russell Y.
SANDLER, Anthony, D.
BOLLARD, Catherine, M.
SWEENEY, Elizabeth, E.
CANO-MEJIA, Juliana
BURGA, Rachel
DUMONT, Matthieu, F.
Title: FUNCTIONALIZED PRUSSIAN BLUE NANOPARTICES, COMBINATION PRUSSIAN BLUE NANOPARTICLE-BASED NANO-IMMUNOTHERAPHY AND APPLICATIONS THEREOF
Abstract:
Combination treatment with Prussian blue nanoparticles and at least one immunotherapeutic treatment. Stable, functionalized Prussian blue nanoparticles, including those with enhanced stability under alkaline conditions, and methods of cancer, neoplasm, and tumor treatment using them, including photothermal treatment and combination immunotherapeutic treatments.