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1. (WO2017156090) METHODS TO TARGET PKD1/PKD2 lON CHANNEL COMPLEX
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Pub. No.: WO/2017/156090 International Application No.: PCT/US2017/021309
Publication Date: 14.09.2017 International Filing Date: 08.03.2017
IPC:
G01N 33/50 (2006.01) ,G01N 33/68 (2006.01) ,C07K 14/47 (2006.01) ,C12N 5/071 (2010.01)
[IPC code unknown for G01N 33/50][IPC code unknown for G01N 33/68][IPC code unknown for C07K 14/47][IPC code unknown for C12N 5/071]
Applicants:
CHILDREN'S MEDICAL CENTER CORPORATION [US/US]; 55 Shattuck Street Boston, MA 02115, US
Inventors:
DELLING, Markus, G.; US
CLAPHAM, David, E.; US
DOERNER, Julia, F.; US
Agent:
LOCKHART, Helen, C.; US
Priority Data:
62/305,16008.03.2016US
62/306,39910.03.2016US
Title (EN) METHODS TO TARGET PKD1/PKD2 lON CHANNEL COMPLEX
(FR) PROCÉDÉS POUR CIBLER UN COMPLEXE CANAL IONIQUE PKD1/PKD2
Abstract:
(EN) Methods for identifying compounds that modulate polycystin-l/polycystin-2 (PKD1/PKD2) ion channel activity or cilium/plasma membrane trafficking are provided. Related reagents and uses of the compounds are also provided.
(FR) L'invention concerne des procédés d'identification de composés qui modulent l'activité du canal ionique de polycystine-l/polycystine -2 (PKD1/PKD2) ou le trafic membranaire cilium/plasma. L'invention concerne également des réactifs associés et des utilisations de ces composés.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)