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1. (WO2017156038) IMMUNOASSAY CONTROLS AND THE USE THEREOF
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Pub. No.: WO/2017/156038 International Application No.: PCT/US2017/021211
Publication Date: 14.09.2017 International Filing Date: 07.03.2017
IPC:
G01N 33/53 (2006.01) ,G01N 33/563 (2006.01) ,G01N 33/68 (2006.01) ,C07K 7/06 (2006.01) ,C07K 16/18 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
563
involving antibody fragments
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
06
having 5 to 11 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
Applicants:
QUIDEL CARDIOVASCULAR INC. [US/US]; 12544 High Bluff Drive, Suite 200 San Diego, CA 92130, US
Inventors:
GARY, Jonathan; US
RONGEY, Scott; US
POWELL, James; US
Agent:
MOHR, Judy M.; US
CHAMBERS, Dan; US
Priority Data:
62/304,76207.03.2016US
62/346,34706.06.2016US
Title (EN) IMMUNOASSAY CONTROLS AND THE USE THEREOF
(FR) ÉTALONS INTERNES POUR DOSAGES IMMUNOLOGIQUES ET LEUR UTILISATION
Abstract:
(EN) The present invention relates to compositions and methods use in designing immunoassay controls. In various aspects, the invention provides synthetic peptides comprising the sequence CPRRPYIL or an analog thereof; ELAGLGFAELQC or an analog thereof; and CDWRKNIDAL or an analog thereof; specific binding reagents that bind to a CPRRPYIL, ELAGLGFAELQC or CDWRKNIDAL peptide; methods of producing such reagents; and assays utilizing such reagents to provide assay controls signals that are unrelated to the measurement of the analyte or analytes of interest in that no reagents used in the analyte assay(s) contribute to the control signal.
(FR) La présente invention concerne des compositions et leur utilisation dans des procédés de conception d'étalons internes pour dosages immunologiques. Selon divers aspects, l'invention concerne des peptides synthétiques comprenant la séquence CPRRPYIL ou un analogue de celle-ci ; ELAGLGFAELQC ou un analogue de celle-ci ; et CDWRKNIDAL ou un analogue de celle-ci ; des réactifs de liaison spécifiques qui se lient à un peptide CPRRPYIL, ELAGGFAELQC ou CDWRKNIDAL ; des procédés de production desdits réactifs ; et des dosages utilisant ces réactifs pour obtenir des signaux d'étalons internes sans rapport avec la mesure du ou des analytes d'intérêt puisqu'aucun des réactifs utilisés dans le dosage dudit ou desdits analytes ne contribue au signal de l'étalon interne.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)