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1. (WO2017155975) BIOMARKERS IN NASAL EXHALED BREATH
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Pub. No.: WO/2017/155975 International Application No.: PCT/US2017/021127
Publication Date: 14.09.2017 International Filing Date: 07.03.2017
IPC:
A61B 5/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
Applicants:
REHABILITATION INSTITUTE OF CHICAGO [US/US]; 345 East Superior Street Chicago, IL 60611, US
NORTHWESTERN UNIVERSITY [US/US]; 633 Clark Street Evanston, IL 60208, US
Inventors:
GRAFMAN, Jordan; US
ZELANO, Christina, M.; US
HAUNER, Katherina, K.; US
Agent:
WULFF, Richard, A.; US
BEYER, Carrie, A.; US
STANTON, Gregory, E.; US
RUPP, Brian, C.; US
WHITE, Henry, Blanco; US
Priority Data:
62/304,88707.03.2016US
Title (EN) BIOMARKERS IN NASAL EXHALED BREATH
(FR) BIOMARQUEURS DANS L'AIR EXPIRÉ NASAL
Abstract:
(EN) A method of diagnosing or assessing risk of a tauopathy in a person is disclosed. The method may comprise collecting a nasal sample of exhaled breath from the person's nose, analyzing the nasal sample to detect the presence of tau protein in the sample, and determining the concentration of tau protein in the nasal sample, wherein the tau protein concentration in the nasal sample indicates susceptibility to the tauopathy.
(FR) L'invention concerne un procédé de diagnostic ou d'évaluation de risque de tauopathie chez une personne. Le procédé peut consister à collecter un échantillon d'air expiré nasal à partir du nez de la personne, à analyser l'échantillon nasal pour détecter la présence de protéine tau dans l'échantillon, et à déterminer la concentration de protéine tau dans l'échantillon nasal, la concentration de protéine tau dans l'échantillon nasal indiquant la sensibilité à la tauopathie.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)