Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2017155958) DYNAMIC UREA BONDS WITH FAST HYDROLYTIC KINETICS FOR POLYMERS
Latest bibliographic data on file with the International Bureau    Submit observation
Pub. No.: WO/2017/155958 International Application No.: PCT/US2017/021105
Publication Date: 14.09.2017 International Filing Date: 07.03.2017
IPC:
C08G 18/32 (2006.01) ,C08G 18/76 (2006.01) ,C08L 75/02 (2006.01) ,A61L 27/18 (2006.01)
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
G
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
18
Polymeric products of isocyanates or isothiocyanates
06
with compounds having active hydrogen
28
characterised by the compounds used containing active hydrogen
30
Low-molecular-weight compounds
32
Polyhydroxy compounds; Polyamines; Hydroxy amines
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
G
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
18
Polymeric products of isocyanates or isothiocyanates
06
with compounds having active hydrogen
70
characterised by the isocyanates or isothiocyanates used
72
Polyisocyanates or polyisothiocyanates
74
cyclic
76
aromatic
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
L
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
75
Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
02
Polyureas
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
14
Macromolecular materials
18
obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
Applicants:
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS [US/US]; 352 Henry Administration Building 506 South Wright Street Urbana, IL 61801, US
Inventors:
CHENG, Jianjun; US
CAI, Kaimin; US
YING, Hanze; US
Agent:
SABATELLI, Anthony, D.; US
Priority Data:
62/304,96408.03.2016US
Title (EN) DYNAMIC UREA BONDS WITH FAST HYDROLYTIC KINETICS FOR POLYMERS
(FR) LIAISONS URÉE DYNAMIQUES À CINÉTIQUE HYDROLYTIQUE RAPIDE POUR POLYMÈRES
Abstract:
(EN) The present invention relates to polymers having dynamic urea bonds and more specifically to polymers having hindered urea bonds (HUBs) with fast hydrolytic kinetics. These urea bonds are ary!-substituted, i.e. aromatic-substituted hindered urea bonds, that demonstrate pH independent hydrolytic kinetics, such that they consistently and rapidly hydroiyze in water from pH 2 to 11. The urea bond dissociation for these materials is generally such that k-1> h-1, which is two orders of magnitudes faster than for aliphatic hindered ureas. The present invention also relates to hydrolytically reversible or degradable linear, branched or network polymers incorporating these HUBs and to precursors for incorporation of these HUBs into these polymers. The technology can be applied to and integrated into a variety of polymers, such as polyureas, polyurethanes, polyesters, polyamides, polycarbonates, polyamines, and polysaccharides to make linear, branched, and cross-linked polymers. Polymers incorporating these HUBs can be used in a wide variety of applications including for example, environmentally compatible packaging materials and biomedical applications, such as drug delivery systems and tissue engineering. In other embodiments, the HUBs can be used in self-healing polymers.
(FR) La présente invention concerne des polymères présentant des liaisons urée dynamiques et, plus spécifiquement, des polymères présentant des liaisons urée encombrées (LUE) à cinétique hydrolytique rapide. Ces liaisons urée sont des liaisons urée encombrées substituées par aryle, c'est-à-dire de manière aromatique, qui présentent une cinétique hydrolytique indépendante du pH, de manière telle qu'elles s'hydrolysent de manière constante et rapide dans de l'eau à pH 2 jusqu'à 11. La dissociation de liaison urée pour ces matériaux est généralement telle que k-1> h-1, ce qui est de deux ordres de grandeur plus rapide que pour les urées encombrées aliphatiques. La présente invention concerne également des polymères linéaires, ramifiés ou réticulés, hydrolytiquement réversibles ou dégradables, incorporant ces LUE et des précurseurs pour l'incorporation de ces LUE dans ces polymères. La technologie peut être appliquée à et intégrée dans divers polymères, tels que les polyurées, les polyuréthanes, les polyesters, les polyamides, les polycarbonates, les polyamines et les polysaccharides, afin de produire des polymères linéaires, ramifiés et réticulés. Les polymères incluant ces LUE peuvent être utilisés dans diverses applications, comprenant par exemple les matériaux d'emballage écologiquement compatibles et les applications biomédicales, tells que des systèmes d'administration de médicaments et l'ingénierie tissulaire. Dans d'autres modes de réalisation, les LUE peuvent être utilisées dans des polymères autoréparants.
 front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)