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1. (WO2017155910) THIAZOLIDINONE COMPOUNDS AND USE THEREOF

Pub. No.:    WO/2017/155910    International Application No.:    PCT/US2017/021033
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Wed Mar 08 00:59:59 CET 2017
IPC: A61K 31/427
C07D 277/02
C07D 417/06
Applicants: SHIH, Chuan
NATIONAL HEALTH RESEARCH INSTITUTES
Inventors: SHIH, Chuan
UENG, Shau-Hua
YEH, Shiu-Hwa
LIN, Shu-Yu
LOH, Horace
Title: THIAZOLIDINONE COMPOUNDS AND USE THEREOF
Abstract:
A pharmaceutical composition containing a compound of Formula (I) for treating an opioid receptor-associated condition. Also disclosed is a method for treating an opioid receptor-associated condition using such a compound. Further disclosed are two sets of thiazolidinone compounds of formula (I): (i) compounds each having an enantiomeric excess greater than 90% and (ii) compounds each being substituted with deuterium.