Search International and National Patent Collections

1. (WO2017155677) THE USE OF A HEMOCOMPATIBLE POROUS POLYMER BEAD SORBENT FOR REMOVAL OF PAMPS AND DAMPS

Pub. No.:    WO/2017/155677    International Application No.:    PCT/US2017/018249
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Sat Feb 18 00:59:59 CET 2017
IPC: A61K 9/18
A61M 1/00
B01J 20/285
B01J 20/22
B01J 20/28
Applicants: CYTOSORBENTS CORPORATION
Inventors: GRUDA, Maryann
O'SULLIVAN, Pamela
GULIASHVILI, Tamaz
SCHEIRER, Andrew
GOLOBISH, Thomas
CAPPONI, Vincent
CHAN, Phillip
Title: THE USE OF A HEMOCOMPATIBLE POROUS POLYMER BEAD SORBENT FOR REMOVAL OF PAMPS AND DAMPS
Abstract:
The invention concerns biocompatible polymer systems comprising at least one polymer sorbent with a plurality of pores, said polymer designed to adsorb pathogen-associated molecular pattern molecules and damage-associated molecular pattern molecules. Also disclosed herein are methods for reducing contamination in a biological substance, or treating contamination in a subject, by one or more pathogen-associated molecular pattern molecules and damage-associated molecular pattern molecules, by contacting the biological substance with an effective amount of sorbent capable of sorbing the toxin.