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1. (WO2017155386) METHOD FOR TREATING BRAIN ATROPHY

Pub. No.:    WO/2017/155386    International Application No.:    PCT/NL2016/050160
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Wed Mar 09 00:59:59 CET 2016
IPC: A61K 31/04
A61K 31/202
A61K 31/375
A61K 31/7068
A61K 31/7072
A61P 25/28
Applicants: N.V. NUTRICIA
Inventors: DE WILDE, Mattheus Comelis
Title: METHOD FOR TREATING BRAIN ATROPHY
Abstract:
The invention pertains to the use of therapeutically effective amounts of (i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof; and(ii) at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof; and (iii) vitamin C and/or selenium, optionally in combination with vitamin E, in the manufacture of a product for therapeutically preventing and/or slowing down brain atrophy in a human subject in need thereof.