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1. (WO2017155283) METHOD FOR QUANTITATIVELY PROBING METAL ION WITHIN LIVING SINGLE CELL, AND NANOWIRE-BASED WAVEGUIDE PROBE FOR USE THEREIN

Pub. No.:    WO/2017/155283    International Application No.:    PCT/KR2017/002458
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Wed Mar 08 00:59:59 CET 2017
IPC: G01N 21/85
G01N 33/487
G01N 33/20
G02B 6/10
Applicants: LESSENGERS INC.
주식회사 레신저스
Inventors: JE, Jung Ho
제정호
LEE, Jun Ho
이준호
Title: METHOD FOR QUANTITATIVELY PROBING METAL ION WITHIN LIVING SINGLE CELL, AND NANOWIRE-BASED WAVEGUIDE PROBE FOR USE THEREIN
Abstract:
The present invention relates to the development of an active nanowire-based waveguide probe, and the quantitative probing of Cu2+ ions naturally present in living single neurons on the basis thereof. Specifically, the present invention allows intracellular Cu2+ ions to be quantitatively measured through the direct observation of photoluminescence (PL) quenching by the Cu2+ ions within the nanowire by inserting a nanowire waveguide probe into living single cells.