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|1. (WO2017155267) SELF-ASSEMBLED NANOPARTICLE RELEASING SOLUBLE MICRONEEDLE STRUCTURE AND PREPARATION METHOD THEREFOR|
|Applicants:||RESEARCH BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
|Inventors:||JEONG, Ji Hoon
KIM, Nak Won
|Title:||SELF-ASSEMBLED NANOPARTICLE RELEASING SOLUBLE MICRONEEDLE STRUCTURE AND PREPARATION METHOD THEREFOR|
The present invention relates to a self-assembled nanoparticle releasing microneedle structure which is formed of biocompatible amphiphilic block copolymers containing a drug, and a preparation method therefor. The microneedle structure according to the present invention can deliver a water-soluble or hydrophobic drug while being carried in a microneedle. In particular, since a fat-soluble drug is delivered while being carried by micelle-type self-assembled nanoparticles which are formed as the structure is dissolved, it is possible to greatly increase the solubility in an aqueous solution. As such, existing drugs with poor absorption can be delivered through the skin of a body.