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1. (WO2017155267) SELF-ASSEMBLED NANOPARTICLE RELEASING SOLUBLE MICRONEEDLE STRUCTURE AND PREPARATION METHOD THEREFOR

Pub. No.:    WO/2017/155267    International Application No.:    PCT/KR2017/002425
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Wed Mar 08 00:59:59 CET 2017
IPC: A61M 37/00
A61L 27/26
A61L 27/54
A61L 27/58
A61K 9/127
A61K 9/00
A61K 39/395
A61K 48/00
Applicants: RESEARCH BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
성균관대학교산학협력단
Inventors: JEONG, Ji Hoon
정지훈
KIM, Nak Won
김낙원
Title: SELF-ASSEMBLED NANOPARTICLE RELEASING SOLUBLE MICRONEEDLE STRUCTURE AND PREPARATION METHOD THEREFOR
Abstract:
The present invention relates to a self-assembled nanoparticle releasing microneedle structure which is formed of biocompatible amphiphilic block copolymers containing a drug, and a preparation method therefor. The microneedle structure according to the present invention can deliver a water-soluble or hydrophobic drug while being carried in a microneedle. In particular, since a fat-soluble drug is delivered while being carried by micelle-type self-assembled nanoparticles which are formed as the structure is dissolved, it is possible to greatly increase the solubility in an aqueous solution. As such, existing drugs with poor absorption can be delivered through the skin of a body.