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1. (WO2017155129) COMPOSITION FOR INDUCING DIFFERENTIATION OF CARDIOMYOCYTE CONTAINING ECHINOCHROME A AS ACTIVE INGREDIENT

Pub. No.:    WO/2017/155129    International Application No.:    PCT/KR2016/002267
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Tue Mar 08 00:59:59 CET 2016
IPC: A61K 35/12
A61K 31/122
A61P 9/10
Applicants: INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
인제대학교 산학협력단
Inventors: HAN, Jin
한진
HEO, Hye Jin
허혜진
KIM, Nari
김나리
KIM, Hyoung Kyu
김형규
Title: COMPOSITION FOR INDUCING DIFFERENTIATION OF CARDIOMYOCYTE CONTAINING ECHINOCHROME A AS ACTIVE INGREDIENT
Abstract:
The present invention relates to a pharmaceutical composition for promoting differentiation of cardiomyocytes derived from embryonic stem cells containing Echinochrome A as an active ingredient. More specifically, since it has been confirmed that Echinochrome A extracted from Plococidaris verticillata of Echinodermata exhibits non-cytotoxicity and effectively induces differentiation from mouse embryonic stem cells into cardiomyocytes, the composition containing Echinochrome A as an active ingredient according to the present invention may be provided as a composition or a medium composition for inducing differentiation of cardiomyocytes.