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1. (WO2017153958) NOVEL POLYMORPHIC FORMS AND AMORPHOUS FORM OF OLAPARIB
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Pub. No.: WO/2017/153958 International Application No.: PCT/IB2017/051407
Publication Date: 14.09.2017 International Filing Date: 10.03.2017
IPC:
C07D 237/32 (2006.01) ,A61K 31/502 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
237
Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
26
condensed with carbocyclic rings or ring systems
30
Phthalazines
32
with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
50
Pyridazines; Hydrogenated pyridazines
502
ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
LUPIN LIMITED [IN/IN]; Kalpataru Inspire, 3rd Floor, Off Western Express Highway, Santacruz (East), Maharashtra, Mumbai 400 055, IN
Inventors:
RAJPUT, Lalitkumar, Dilipsing; IN
SHIVDAVKAR, Radhakrishna, Bhikaji; IN
SINGH, Gurvinder, Pal; IN
RAY, Purna, Chandra; IN
SINGH, Girij, Pal; IN
Agent:
MAJUMDAR, Subhatosh; IN
GANGULI, Dr., Sanchita; IN
SEN, Abhishek; IN
VENKATESH, Mythili; IN
MAJUMDAR, Amrita; IN
KUNDU, Subarna; IN
CHAUBEY, Priyanka; IN
Priority Data:
20162100866211.03.2016IN
Title (EN) NOVEL POLYMORPHIC FORMS AND AMORPHOUS FORM OF OLAPARIB
(FR) NOUVELLES FORMES POLYMORPHES ET FORME AMORPHE D'OLAPARIB
Abstract:
(EN) The present invention provides crystalline Form M of Olaparib, amorphous form of Olaparib, process for their preparation, pharmaceutical composition thereof and their use as medicaments.
(FR) La présente invention concerne une forme cristalline M d'olaparib, une forme amorphe d'olaparib, un procédé pour leur préparation, une composition pharmaceutique de ceux-ci et leur utilisation comme médicaments. 5
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)