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1. (WO2017153933) ABUSE-RESISTANT PHARMACEUTICAL FORMULATIONS
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Pub. No.: WO/2017/153933 International Application No.: PCT/IB2017/051362
Publication Date: 14.09.2017 International Filing Date: 08.03.2017
IPC:
A61K 9/48 (2006.01) ,A61K 31/485 (2006.01)
[IPC code unknown for A61K 9/48][IPC code unknown for A61K 31/485]
Applicants:
INDIVIOR UK LIMITED [GB/GB]; 103-105 Bath Road Slough Berkshire SL1 3UH, GB
Inventors:
YOUNG, Victor, Morrison; GB
FORBES, Michael; GB
MCNAUGHTON, Alyn, Brandon; GB
Agent:
HGF GMBH; OBC Suisse AG Basel-City Aeschenvorstadt 71 4051 Basel, CH
Priority Data:
62/305,93709.03.2016US
Title (EN) ABUSE-RESISTANT PHARMACEUTICAL FORMULATIONS
(FR) COMPOSITIONS PHARMACEUTIQUES ANTI-ABUS
Abstract:
(EN) The disclosure provides orally administrable capsules comprising abuse-resistant, pharmaceutical formulations which comprise abuse-susceptible active agents such as opioids. The formulations provide abuse resistance by having a sufficiently high viscosity that substantially prevents the formulation and opioid therein, from being drawn into a syringe, at room temperature or higher, either alone or when mixed with water or other liquids.
(FR) L'invention concerne des gélules pouvant être administrées par voie orale et comprenant des compositions pharmaceutiques anti-abus qui contiennent des agents actifs susceptibles de faire l'objet d'un usage abusif tels que des opioïdes. Ces compositions ont un effet anti-abus car elles présentent une viscosité suffisamment élevée pour empêcher sensiblement l'aspiration de la composition renfermant l'opioïde dans une seringue, à température ambiante ou à une température plus élevée, soit seule soit mélangée avec de l'eau ou d'autres liquides.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)