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1. (WO2017153922) DETECTION OF NEURODEGENERATIVE DISEASES
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Pub. No.: WO/2017/153922 International Application No.: PCT/IB2017/051343
Publication Date: 14.09.2017 International Filing Date: 07.03.2017
IPC:
C07F 5/02 (2006.01) ,G01N 21/64 (2006.01) ,G01N 33/53 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
5
Compounds containing elements of the 3rd Group of the Periodic System
02
Boron compounds
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
62
Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63
optically excited
64
Fluorescence; Phosphorescence
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
Applicants:
AMONETA DIAGNOSTICS SAS [FR/FR]; 17 rue du Fort 68330 Huningue, FR
JPT PEPTIDE TECHNOLOGIES GMBH [DE/DE]; Volmerstrasse 5 12489 Berlin, DE
CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE [FR/FR]; 3, rue Michel Ange 75794 Paris Cedex 16, FR
UNIVERSITÉ DE STRASBOURG [FR/FR]; 4, rue Blaise Pascal 67081 Strasbourg Cedex, FR
Inventors:
MOUSSAOUI, Saliha; FR
WILDEMANN, Dirk; DE
WENSCHUH, Holger; DE
SCHNATBAUM, Karsten; DE
ULRICH, Gilles; FR
DE BARRY, Jean; FR
MBEBI-LIEGEOIS, Corinne; FR
FIRAT, Hueseyin; FR
Agent:
PHARMA CONCEPTS GMBH; Unterer Rheinweg 50 4057 Basel, CH
Priority Data:
62/304,86407.03.2016US
Title (EN) DETECTION OF NEURODEGENERATIVE DISEASES
(FR) DÉPISTAGE DE MALADIES NEURODÉGÉNÉRATIVES
Abstract:
(EN) The present invention relates to novel compounds, their uses as biomarker, and/or methods including a non-invasive in vitro method using this biomarker, for diagnosing or monitoring the development or the progression of Alzheimer's disease (AD) or a disease or disorder associated with β-amyloid peptide (Aβ) deposition or tau hyperphosphorylation or a disease or disorder characterized by a proteinopathy implicating abnormalities in protein kinase C (PKC).
(FR) La présente invention concerne de nouveaux composés, leurs utilisations en tant que biomarqueur, et/ou des méthodes comprenant une méthode in vitro non invasive utilisant ce biomarqueur, pour diagnostiquer ou surveiller le développement ou la progression de la maladie d'Alzheimer (AD) ou une maladie ou un trouble associé au dépôt de peptide bêta-amyloïde (Aβ) ou à une hyperphosphorylation de tau ou une maladie ou un trouble caractérisé par une protéinopathie impliquant des anomalies dans la protéine kinase C (PKC).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)