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1. (WO2017153849) ALGORITHM AND AN IN VITRO METHOD BASED ON RNA EDITING TO SELECT PARTICULAR EFFECT INDUCED BY ACTIVE COMPOUNDS

Pub. No.:    WO/2017/153849    International Application No.:    PCT/IB2017/000417
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Tue Mar 14 00:59:59 CET 2017
IPC: C12Q 1/68
G06F 19/16
Applicants: ALCEDIAG
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Inventors: WEISSMANN, Dinah
VAN DER LAAN, Siem
SALVETAT, Nicolas
MOLINA, Franck
PUJOL, Jean-François
Title: ALGORITHM AND AN IN VITRO METHOD BASED ON RNA EDITING TO SELECT PARTICULAR EFFECT INDUCED BY ACTIVE COMPOUNDS
Abstract:
The present invention is drawn to an algorithm and method using the same algorithm for in vitro predicting the probability of a drug or a compound to induce a particular effect in a patient, said method using at least one target exhibiting an A-to-I editing of RNA. The present invention also relates to kits for the implementation of the method.