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1. (WO2017153748) INDOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS

Pub. No.:    WO/2017/153748    International Application No.:    PCT/GB2017/050619
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Thu Mar 09 00:59:59 CET 2017
IPC: C07D 403/12
C07D 401/12
C07D 471/10
C07D 209/34
C07D 295/145
A61K 31/404
A61P 11/00
C07C 205/57
Applicants: RESPIVERT LIMITED
Inventors: WALTERS, Iain
BIRCH, Louise
COLLINGWOOD, Stephen, Paul
STEVENSON, Christopher, Scott
Title: INDOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS
Abstract:
The present invention relates inter alia to a compound of formula (I) wherein R1, R2 and R3, are as defined in the specification and to compositions comprising the same and to the use of the compounds and to compositions of the compounds in treatment, for example in the treatment of fibrotic diseases or interstitial lung diseases, in particular idiopathic pulmonary fibrosis.