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1. (WO2017153734) METHOD AND MICROBES FOR THE PRODUCTION OF CHIRAL COMPOUNDS
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Pub. No.: WO/2017/153734 International Application No.: PCT/GB2017/050601
Publication Date: 14.09.2017 International Filing Date: 07.03.2017
IPC:
C12N 15/52 (2006.01)
[IPC code unknown for C12N 15/52]
Applicants:
CHAIN BIOTECHNOLOGY LIMITED [GB/GB]; James Cowper LLP 2 Chawley Park Cumnor Hill Oxford Oxfordshire OX2 9GG, GB
Inventors:
GREEN, Edward; GB
HELDT, Dana; GB
BRADLEY, Benjamin; GB
Agent:
CALLAGHAN, Dayle Anne; GB
Priority Data:
1603915.807.03.2016GB
Title (EN) METHOD AND MICROBES FOR THE PRODUCTION OF CHIRAL COMPOUNDS
(FR) PROCÉDÉ ET MICROBES POUR LA PRODUCTION DE COMPOSÉS CHIRAUX
Abstract:
(EN) The present invention provides a Clostridiumspecies comprising a non-native gene capable of expressing (R)-3-hydroxybutyryl-Co A dehydrogenase. Also provided is a method of producing (R)-3-hydroxybutyric acid, or a salt thereof, and/or (R) 1,3-butanediol using such Clostridium.
(FR) La présente invention concerne une bactérie du genre Clostridium comprenant un gène non natif capable d'exprimer la (R)-3-hydroxybutyryl-Co A déshydrogénase. L'invention concerne également un procédé pour produire l'acide (R)-3-hydroxybutyrique, ou un sel correspondant, et/ou le (R) 1,3-butanediol en utilisant ladite bactérie du genre Clostridium.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)