The present invention provides hybrid nanofibres that comprise a mixture of components of an Aloe vera gel and a synthetic polymer selected from poly-3-hydroxybutyrate-co-3-hydroxyvalerate (PHBV), poly-L-lactic acid (PLLA) and polydioxanone (PDS), the average diameter of the hybrid nanofibres being 0.3 to 1.5 microns. The invention also relates to hybrid nanofibres that comprise a mixture of components of a bee honey and a synthetic honey. The invention further provides a method for producing the hybrid nanofibres. The hybrid nanofibres of the invention can be used in tubular prostheses for nerve reconnection following peripheral nerve axotomy, in surgical meshes, dressings and sutures, to improve the reinnervation, and therefore the functional recovery from injuries in diverse organs such as the skin (e.g. burns, ulcers, surgical incisions, fistulas, etc. ).