Search International and National Patent Collections

1. (WO2017153475) TOTAL CELLULAR IRON AS A MARKER OF CANCER STEM CELLS AND USES THEREOF

Pub. No.:    WO/2017/153475    International Application No.:    PCT/EP2017/055450
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Thu Mar 09 00:59:59 CET 2017
IPC: G01N 33/574
G01N 33/50
G01N 33/84
Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
UNIVERSITE PARIS DESCARTES
Inventors: MEHRPOUR, Maryam
RODRIGUEZ, Raphael
HAMAI, Ahmed
TRANG, Mai
Title: TOTAL CELLULAR IRON AS A MARKER OF CANCER STEM CELLS AND USES THEREOF
Abstract:
The present invention relates to a novel use of total cellular iron, preferably under the form of ferrous iron (Fe2+), as a marker of cancer stem cells (CSCs). The invention also relates to methods using said iron marker, in particular for metastatic cancer diagnosis or treatment, for screening for compounds of interest, as well as for killing CSCs.