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1. (WO2017153231) SUBSTITUTED N-CYCLO-2-ARYL-ISOQUINOLINONE-4-CARBOXAMIDES AND USE THEREOF
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Pub. No.: WO/2017/153231 International Application No.: PCT/EP2017/054866
Publication Date: 14.09.2017 International Filing Date: 02.03.2017
IPC:
C07D 217/26 (2006.01) ,A61K 31/472 (2006.01) ,A61P 11/00 (2006.01)
[IPC code unknown for C07D 217/26][IPC code unknown for A61K 31/472][IPC code unknown for A61P 11]
Applicants:
BAYER PHARMA AKTIENGESELLSCHAFT [DE/DE]; Müllerstr. 178 13353 Berlin, DE
Inventors:
BECK, Hartmut; DE
THALER, Tobias; DE
KAST, Raimund; DE
MEININGHAUS, Mark; DE
TERJUNG, Carsten; DE
MIYATAKE ONDOZABAL, Hideki; DE
Agent:
BIP PATENTS; Alfred-Nobel-Str. 10 40789 Monheim am Rhein NRW, DE
Priority Data:
16159493.209.03.2016EP
Title (EN) SUBSTITUTED N-CYCLO-2-ARYL-ISOQUINOLINONE-4-CARBOXAMIDES AND USE THEREOF
(FR) N-CYCLO-2-ARYLISOCHINOLINON-4-CARBOXAMIDES SUBSTITUÉS ET LEUR UTILISATION
(DE) SUBSTITUIERTE N-CYCLO-2-ARYLISOCHINOLINON-4-CARBOXAMIDE UND IHRE VERWENDUNG
Abstract:
(EN) The invention relates to new substituted N-cyclo-2-aryl-isoquinolinone-4-carboxamide derivatives, to methods for the production thereof, to the use thereof either alone or in combination for treating and/or preventing diseases and to their use for producing drugs for treating and/or preventing diseases, particularly for the treatment and/or prevention of fibrotic and inflammatory diseases.
(FR) L'invention concerne de nouveaux dérivés de N-cyclo-2-arylisochinolinon-4-carboxamides substitués, des procédés de préparation de ces composés, leur utilisation seuls ou dans des combinaisons pour le traitement et/ou la prévention de maladies, et leur utilisation pour la fabrication de médicaments pour le traitement et/ou la prévention de maladies, notamment pour le traitement et/ou la prévention de maladies fibrotiques et inflammatoires.
(DE) Die vorliegende Anmeldung betrifft neue substituierte N-Cyclo-2-arylisochinolinon-4-carbox- amid-Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung allein oder in Kombinationen zur Behandlung und/oder Prävention von Krankheiten sowie ihre Verwendung zur Herstellung von Arzneimitteln zur Behandlung und/oder Prävention von Krankheiten, insbesondere zur Behandlung und/oder Prävention von fibrotischen und inflammatorischen Erkrankungen.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)