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1. (WO2017152918) SEPARATION OF OLIGOSACCHARIDES FROM FERMENTATION BROTH
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Pub. No.: WO/2017/152918 International Application No.: PCT/DK2017/050063
Publication Date: 14.09.2017 International Filing Date: 07.03.2017
IPC:
C07H 1/06 (2006.01)
[IPC code unknown for C07H 1/06]
Applicants:
GLYCOM A/S [DK/DK]; Kogle Allé 4 2970 Hørsholm, DK
Inventors:
MATWIEJUK, Martin; DE
KHANZHIN, Nikolay; DK
CHASSAGNE, Pierre; FR
HEDEROS, Markus; SE
Agent:
THORSEN, Jesper; DK
FREDERIKSEN, Jakob; DK
HANSEN, Carsten; DK
HERTLING, Peter; DK
KLINGE, Ulla; DK
KOEFOED, Peter; DK
MADSEN, Steen; DK
SIMONSEN, Jan; DK
STAHR, Pia; DK
THEIL, Christa; DK
HAMMER, Velaja Bisgaard; DK
LÖVQVIST, Anna; DK
HERTLING, Christina E.; DK
FARRINGTON, Edward; DK
Priority Data:
PA 2016 7013107.03.2016DK
Title (EN) SEPARATION OF OLIGOSACCHARIDES FROM FERMENTATION BROTH
(FR) SÉPARATION D'OLIGOSACCHARIDES DANS UN BOUILLON DE FERMENTATION
Abstract:
(EN) The present invention relates to a method for separating sialylated oligosaccharides from a fermentation broth in which they are produced by a genetically modified microorganism The separation comprises the steps of: i) ultrafiltration; ii) nanofiltration; iii) optionally, activated charcoal treatment; and iv) treatment with strong anion and/or cation exchange resin.
(FR) La présente invention concerne un procédé de séparation d'oligosaccharides sialylés dans un bouillon de fermentation dans lequel ils sont produits par un microorganisme génétiquement modifié. La séparation comprend les étapes suivantes : i) ultrafiltration ; ii) nanofiltration ; iii) traitement éventuel au charbon actif ; et iv) traitement avec une résine forte échangeuse d'anions et/ou de cations.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)