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1. (WO2017152725) RETINOID COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATES THEREOF AND APPLICATION THEREOF
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Pub. No.: WO/2017/152725 International Application No.: PCT/CN2017/071922
Publication Date: 14.09.2017 International Filing Date: 20.01.2017
IPC:
C07D 335/06 (2006.01) ,C07D 409/06 (2006.01) ,C07C 69/84 (2006.01) ,C07D 239/28 (2006.01) ,C07D 213/85 (2006.01) ,A61K 31/382 (2006.01) ,A61K 31/506 (2006.01) ,A61K 31/235 (2006.01) ,A61P 35/00 (2006.01) ,A61P 35/02 (2006.01) ,A61P 17/10 (2006.01)
[IPC code unknown for C07D 335/06][IPC code unknown for C07D 409/06][IPC code unknown for C07C 69/84][IPC code unknown for C07D 239/28][IPC code unknown for C07D 213/85][IPC code unknown for A61K 31/382][IPC code unknown for A61K 31/506][IPC code unknown for A61K 31/235][IPC code unknown for A61P 35][IPC code unknown for A61P 35/02][IPC code unknown for A61P 17/10]
Applicants:
中国科学院上海有机化学研究所 SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES [CN/CN]; 中国上海市 徐汇区零陵路345号 345, Lingling Road, Xuhui District Shanghai 200032, CN
华中科技大学 HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY [CN/CN]; 中国湖北省武汉市 洪山区珞喻路1037号 1037, Luoyu Road, Hongshan District Wuhan, Hubei 430074, CN
Inventors:
曹鑫 CAO, Xin; CN
俞飚 YU, Biao; CN
汪宁 WANG, Ning; CN
陈俊威 CHEN, Junwei; CN
Agent:
上海弼兴律师事务所 SHANGHAI BESHINING LAW OFFICE; 中国上海市 小木桥路681号外经大厦21楼 21st Floor, SFECO Mansion, No.681 Xiaomuqiao Road Shanghai 200032, CN
Priority Data:
201610141143.311.03.2016CN
201610310944.811.05.2016CN
Title (EN) RETINOID COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATES THEREOF AND APPLICATION THEREOF
(FR) COMPOSÉ RÉTINOÏDE, SON PROCÉDÉ DE PRÉPARATION, SES INTERMÉDIAIRES ET APPLICATION CORRESPONDANTE
(ZH) 一种视黄酸类化合物、其制备方法、中间体及应用
Abstract:
(EN) Disclosed are a retinoid compound, a preparation method therefor, intermediates thereof and an application thereof. The retinoid compound I of the present invention has a good tumor growth inhibition rate.
(FR) La présente invention concerne un composé rétinoïde, son procédé de préparation, ses intermédiaires et une application correspondante. Le composé rétinoïde I de la présente invention présente un bon taux d'inhibition de la croissance tumorale.
(ZH) 本发明公开了一种视黄酸类化合物、其制备方法、中间体及应用。本发明的视黄酸类化合物I对肿瘤细胞的抑制率较佳。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)