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1. (WO2017152272) MONTELUKAST TRANSMUCOSAL FILM

Pub. No.:    WO/2017/152272    International Application No.:    PCT/CA2017/050267
Publication Date: Fri Sep 15 01:59:59 CEST 2017 International Filing Date: Thu Mar 02 00:59:59 CET 2017
IPC: A61K 9/70
A61K 31/47
A61K 47/34
A61K 47/36
A61K 9/00
C07D 215/18
Applicants: INTELGENX CORP.
Inventors: CONWAY, Justin
OBEID, Rodolphe
PAIEMENT, Nadine
ZERBE, Horst
Title: MONTELUKAST TRANSMUCOSAL FILM
Abstract:
An oral film product in which a pharmaceutically active agent is stabilized in its partially-ionized form to better facilitate oral transmucosal delivery is provided. The film includes a bioadhesive layer including a pharmaceutically active agent having a logarithmic acid dissociation constant that is less than 4.5 and which is complexed with a cationic polymer.