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1. (WO2017152146) COMPOSITIONS AND METHODS FOR INDUCING HIV-1 ANTIBODIES
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Pub. No.: WO/2017/152146 International Application No.: PCT/US2017/020823
Publication Date: 08.09.2017 International Filing Date: 03.03.2017
IPC:
A61K 39/12 (2006.01) ,A61K 9/127 (2006.01) ,C07K 14/16 (2006.01) ,C12Q 1/68 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005
from viruses
08
RNA viruses
15
Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
155
Lentiviridae, e.g. human immunodeficiency virus (HIV), visna-maedi virus, equine infectious anaemia virus
16
HIV-1
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
DUKE UNIVERSITY [US/US]; 2812 Erwin Road Suite 306 Durham, NC 27705, US
LOS ALAMOS NATIONAL SECURITY, LLC [US/US]; Los Alamos National Laboratory LC/TAS P.O. Box 1663 Los Alamos, NM 87545, US
Inventors:
HAYNES, Barton, F.; US
BONSIGNORI, Mattia; US
KORBER, Bette, T.; US
HRABER, Peter, T.; US
SAUNDERS, Kevin; US
Agent:
KIM, William, W.; US
ALLEN, Owen, K.; US
BARAZESH, Ellyar, Y.; US
BEVILACQUA, Michael, J.; US
ANDERSON, Thomas; US
Priority Data:
62/303,27303.03.2016US
62/403,64903.10.2016US
Title (EN) COMPOSITIONS AND METHODS FOR INDUCING HIV-1 ANTIBODIES
(FR) COMPOSITIONS ET PROCÉDÉS POUR INDUIRE DES ANTICORPS DU VIH-1
Abstract:
(EN) In certain aspects the invention provides HIV-1 immunogens, including envelopes (CH0848) and selections therefrom, and methods for swarm immunizations using combinations of HIV- 1 envelopes.
(FR) Selon certains aspects, l'invention concerne des immunogènes du VIH-1, y compris des enveloppes (CH0848) et des sélections de ces dernières, et des procédés d'immunisation d'essaim à l'aide de combinaisons d'enveloppes de VIH-1.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)