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1. (WO2017152085) COMBINATION THERAPY WITH ANTI-CD73 ANTIBODIES

Pub. No.:    WO/2017/152085    International Application No.:    PCT/US2017/020714
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Sat Mar 04 00:59:59 CET 2017
IPC: C07K 16/28
A61K 39/00
Applicants: BRISTOL-MYERS SQUIBB COMPANY
Inventors: BARNHART, Bryan, C.
KORMAN, Alan, J.
LONBERG, Nils
YAMNIUK, Aaron, P.
SRIVISAN, Mohan
HENNING, Karla, A.
LEI, Ming
SEGA, Emanuela
GOODENOUGH, Angela
JURE-KUNKEL, Maria
CHEN, Guodong
SACK, John, S.
HUANG, Richard, Y.
CORBETT, Martin, J.
MYERS, Joseph, E. Jr.
SCHWEIZER, Liang
HATCHER, Sandra, V.
ALTURA, Rachel
HUANG, Haichun
ZHANG, Pingping
HILT, Edward, J.
HEDRICK, Michael, Nathan
Title: COMBINATION THERAPY WITH ANTI-CD73 ANTIBODIES
Abstract:
Provided are methods for clinical treatment of tumors (e.g., advanced solid tumors) using an anti-CD73 antibody in combination with an immuno-oncology agent, such as an anti-PD- 1 antibody.