Search International and National Patent Collections
|1. (WO2017152039) PROTECTION AND DELIVERY OF MULTIPLE THERAPEUTIC PROTEINS|
|Applicants:||UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
|Inventors:||JEFFRIES, Eric, M.
JOHNSON, Noah, R.
|Title:||PROTECTION AND DELIVERY OF MULTIPLE THERAPEUTIC PROTEINS|
Compositions are provided herein comprising a coacervate of a polycationic polymer, a polyanionic polymer, and platelet-rich plasma and/or serum, or a fraction or concentrate thereof. The composition is useful in wound healing. Compositions also are provided that comprise a hydrogel comprising TIMP-3; and a complex of a polycationic polymer, a polyanionic polymer, FGF-2 and SDF-1α embedded in the hydrogel, which is useful in treating a myocardial infarction.