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1. (WO2017152024) BIOMIMETIC POLYMERS FOR THE PREVENTION AND TREATMENT OF VIRAL DISEASES

Pub. No.:    WO/2017/152024    International Application No.:    PCT/US2017/020612
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Sat Mar 04 00:59:59 CET 2017
IPC: A61K 35/76
A61K 39/12
B01J 20/26
B01J 20/285
A61P 31/12
A61P 31/14
A61P 31/20
Applicants: RENSAVIR, INC.
Inventors: MARTIN, Mark, T.
REES, Anthony, R.
Title: BIOMIMETIC POLYMERS FOR THE PREVENTION AND TREATMENT OF VIRAL DISEASES
Abstract:
Antiviral biomimetic polymers (ABPs) are disclosed that can be used to prevent and/or treat viral disease. The ABPs are discovered by a process involving high-throughput screening of polymer libraries using disease- relevant bioactive molecules as target molecules. ABPs can be nanoscale (termed nanoABPs) or larger. Methods are described for the preparation and use of ABPs as prophylactics and therapeutics (in vivo) and as preventative agents, for example, in personal protective equipment (ex vivo). ABPs can be used to prevent and treat viral diseases including those caused by Filoviridae.