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1. (WO2017151983) OSMOTIC DRUG DELIVERY DEVICES AND METHODS OF MAKING OSMOTIC DRUG DELIVERY DEVICES

Pub. No.:    WO/2017/151983    International Application No.:    PCT/US2017/020536
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Fri Mar 03 00:59:59 CET 2017
IPC: A61K 9/00
A61M 31/00
Applicants: TARIS BIOMEDICAL LLC
Inventors: LEE, Heejin
Title: OSMOTIC DRUG DELIVERY DEVICES AND METHODS OF MAKING OSMOTIC DRUG DELIVERY DEVICES
Abstract:
A drug delivery device is provided. In an embodiment, the device includes a polymeric wall structure which includes a first wall portion and an adjacent second wall portion, wherein the first and second wall portions have been co-extruded to define and bound a drug reservoir space. A drug is contained in the drug reservoir space. The device includes an aperture that is in fluid communication with the drug reservoir space. The first and second wall portions are impermeable to the drug. The first wall portion is water impermeable, and the second wall portion is water permeable and configured to permit water in vivo to diffuse into the drug reservoir space and produce an osmotic pressure for driving release of the drug through the aperture.