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1. (WO2017151971) METHODS RELATED TO ENGINEERED Fc CONSTRUCTS

Pub. No.:    WO/2017/151971    International Application No.:    PCT/US2017/020519
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Fri Mar 03 00:59:59 CET 2017
IPC: C12N 9/00
C12N 9/96
G01N 33/53
G01N 33/574
A61P 37/04
C07K 16/28
C07K 16/46
C07K 16/08
C07K 16/12
Applicants: MOMENTA PHARMACEUTICALS, INC.
Inventors: BOSQUES, Carlos, J.
HUSTON, James, S.
LANSING, Jonathan, C.
LING, Leona, E.
MEADOR III, James
ORTIZ, Daniel
RUTITZKY, Laura
SCHULTES, Birgit, C.
Title: METHODS RELATED TO ENGINEERED Fc CONSTRUCTS
Abstract:
The present invention relates to methods of using biologically active Fc domain-containing therapeutic constructs (Fc constructs) to induce immune cell activation of the immune response in a subject, and for example, to treat diseases such as cancers and infections in a subject. Such Fc constructs may include 5 or more Fc domains.