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1. (WO2017151893) TOPICAL ANNESTHETIC COMPOSITION
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Pub. No.: WO/2017/151893 International Application No.: PCT/US2017/020411
Publication Date: 08.09.2017 International Filing Date: 02.03.2017
IPC:
A61K 31/24 (2006.01) ,A61K 31/245 (2006.01) ,A61K 47/10 (2017.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
235
having an aromatic ring attached to a carboxyl group
24
having an amino or nitro group
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
235
having an aromatic ring attached to a carboxyl group
24
having an amino or nitro group
245
Amino benzoic acid types, e.g. procaine, novocaine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
Applicants:
CETYLITE INDUSTRIES, INC. [US/US]; 9051 River Road Pennsauken, New Jersey 08110, US
Inventors:
GWOZDZ, Garry; US
Agent:
AMERNICK, Burton, A.; US
Priority Data:
15/061,28104.03.2016US
Title (EN) TOPICAL ANNESTHETIC COMPOSITION
(FR) COMPOSITION ANESTHÉSIQUE TOPIQUE
Abstract:
(EN) A topical anesthetic composition comprising benzocaine, pharmaceutically acceptable salt thereof, amide thereof and/or ester thereof; tetracaine and/or pharmaceutically acceptable salt thereof; ethanol; polyethylene glycol; propylene glycol; water; and benzyl alcohol is provided. Also provided is method for dispensing the above topical anesthetic composition to a desired site such by spraying the topical anesthetic from a pump actuated metered dose spray device. The topical anesthetic composition can also be administered subgingivally with a syringe and applicator tip. A product comprising the above topical anesthetic spray composition contained in a pump actuated metered dose spray device.
(FR) La présente invention concerne une composition anesthésique topique comprenant de la benzocaïne, un sel pharmaceutiquement acceptable de celle-ci, un amide de celle-ci et/ou un ester de celle-ci ; de la tétracaïne et/ou un sel pharmaceutiquement acceptable de celle-ci ; de l'éthanol ; du polyéthylène glycol ; du propylène glycol ; de l'eau et de l'alcool benzylique. L'invention concerne également une méthode de distribution de la composition anesthésique topique ci-dessus au niveau d'un site souhaité, par exemple en pulvérisant l'anesthésique topique à partir d'un dispositif doseur de pulvérisation actionné par une pompe. La composition anesthésique topique peut également être administrée sous la gencive avec une seringue et une pointe d'applicateur. L'invention concerne en outre un produit comprenant la composition anesthésique topique ci-dessus à pulvériser contenue dans un dispositif doseur de pulvérisation actionné par une pompe.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)