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1. (WO2017151892) IDENTIFICATION AND QUANTIFICATION OF CONJUGATED PEPTIDES IN ANTIBODY DRUG CONJUGATES BY MASS SPECTROMETRY

Pub. No.:    WO/2017/151892    International Application No.:    PCT/US2017/020410
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Fri Mar 03 00:59:59 CET 2017
IPC: G01N 30/72
G01N 33/68
Applicants: WATERS TECHNOLOGIES CORPORATION
Inventors: CHEN, Liuxi
CHEN, Weibin
CUBBEDGE, Steven
Title: IDENTIFICATION AND QUANTIFICATION OF CONJUGATED PEPTIDES IN ANTIBODY DRUG CONJUGATES BY MASS SPECTROMETRY
Abstract:
The present disclosure relates to a streamlined, complete workflow for the qualitative and the quantitative analysis of conjugated peptides from antibody-drug conjugate (ADC) compounds.