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1. (WO2017151862) MATRIX BOUND NANOVESICLES AND THEIR USE

Pub. No.:    WO/2017/151862    International Application No.:    PCT/US2017/020360
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Fri Mar 03 00:59:59 CET 2017
IPC: A61K 9/133
A61P 35/00
A61P 17/02
Applicants: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
Inventors: BADYLAK, Stephen, Francis
HULEIHEL, Luai
HUSSEY, George, S.
NARANJO GUTIERREZ, Juan, Diego
Title: MATRIX BOUND NANOVESICLES AND THEIR USE
Abstract:
A composition is disclosed herein that includes isolated ECM-derived nanovesicles and a pharmaceutically acceptable carrier. Methods are producing the ECM-derived nanovesicles are also disclosed. These ECM-derived nanovesicles can be included in pharmaceutical compositions, bioscaffolds, and devices. Methods for using these ECM-derived nanovesicles are provided.