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1. (WO2017151830) IMMUNOMODULATORS

Pub. No.:    WO/2017/151830    International Application No.:    PCT/US2017/020304
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Fri Mar 03 00:59:59 CET 2017
IPC: C07K 7/08
C07K 7/56
G01N 33/574
A61K 39/39
Applicants: BRISTOL-MYERS SQUIBB COMPANY
Inventors: ALLEN, Martin Patrick
GILLIS, Eric P.
LANGLEY, David R.
MILLER, Michael Matthew
MULL, Eric
SUN, Li-Qiang
YEUNG, Kap-Sun
GRANT-YOUNG, Katharine A.
MEANWELL, Nicholas A.
SCOLA, Paul Michael
Title: IMMUNOMODULATORS
Abstract:
The present disclosure provides novel macrocyclic compounds which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.