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1. (WO2017151755) BIOMARKERS AND METHODS FOR PREDICTING RESPONSE TO DISCONTINUATION OF INFLAMMATORY DISEASE THERAPY

Pub. No.:    WO/2017/151755    International Application No.:    PCT/US2017/020181
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Thu Mar 02 00:59:59 CET 2017
IPC: G01N 33/564
G01N 33/68
Applicants: DEFRANOUX, Nadine
HWANG, Ching-chang
LI, Wanying
TANAKA, Yoshiya
CRESCENDO BIOSCIENCE
UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, JAPAN
Inventors: DEFRANOUX, Nadine
HWANG, Ching-chang
LI, Wanying
TANAKA, Yoshiya
Title: BIOMARKERS AND METHODS FOR PREDICTING RESPONSE TO DISCONTINUATION OF INFLAMMATORY DISEASE THERAPY
Abstract:
Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to predict flare and sustained remission. The methods further include recommending discontinuation of a therapeutic regimen, or no change in a therapeutic regimen, based on the predictions generated by the quantitative data.