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1. (WO2017151563) METHODS OF TREATING AND PREVENTING DISEASE BY CLAMPING OF SKIN

Pub. No.:    WO/2017/151563    International Application No.:    PCT/US2017/019855
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Wed Mar 01 00:59:59 CET 2017
IPC: A61B 17/122
A61B 17/22
A61B 17/30
B25B 7/18
Applicants: NATURAL PHARMACIA INTERNATIONAL, INC.
Inventors: LEE, David, Yue-Wei
CHEN, Long, Zhang
Title: METHODS OF TREATING AND PREVENTING DISEASE BY CLAMPING OF SKIN
Abstract:
The invention provides methods of treating diseases, such as various cancers, neoplasms, autoimmune diseases, and infectious diseases, among others, by clamping the skin of a subject in need of treatment so as to apply a compressive force that is sufficient to cause damage, often manifested in pain or bruising, to the underlying tissue. The invention additionally provides kits containing clamps capable of regulating the distance between the arms of the clamp such that a user of the clamp will apply a safe amount of pressure to the skin of a subject that is sufficient to cause tissue bruising and/or pain.