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1. (WO2017151120) COMPOSITIONS AND METHODS FOR TREATMENT OF INFLUENZA VIRUS

Pub. No.:    WO/2017/151120    International Application No.:    PCT/US2016/020292
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Wed Mar 02 00:59:59 CET 2016
IPC: A61K 31/35
A61K 31/19
A61K 31/13
A61K 31/7048
A61K 31/192
A61K 31/4439
A61P 31/16
Applicants: EMERGING VIRAL THERAPEUTICS (HK) LIMITED
Inventors: HUNG, Ivan
TO, Kelvin
ZHANG, Anna
CHAN, Jasper
FOK, Manson
LAU, Johnson
YUEN, Kwok-Yung
Title: COMPOSITIONS AND METHODS FOR TREATMENT OF INFLUENZA VIRUS
Abstract:
Therapy for influenza using a combination of a neuraminidase inhibitor, a macrolide antibiotic, and a non-steroidal anti-inflammatory drug has been found to provide improved clinical outcomes and reduced incidence of viral quasispecies compared to conventional treatment with neuraminidase inhibitors alone. Effective treatment schedules are also provided. The drug combination can be used in concert with a proton-pump inhibitor and/or an additional antibacterial antibiotic.