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1. (WO2017151072) PRIMER SET FOR NAT2 DIPLOTYPING

Pub. No.:    WO/2017/151072    International Application No.:    PCT/TH2017/000014
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Sat Feb 25 00:59:59 CET 2017
IPC: C12Q 1/68
C12N 15/11
Applicants: DEPARTMENT OF MEDICAL SCIENCES (DMSC)
Inventors: WICHUKCHINDA, Nuanjun
MAHASIRIMONGKOL, Surakameth
TOKUNAGA, Katsushi
TOYO-OKA, Rihito
Title: PRIMER SET FOR NAT2 DIPLOTYPING
Abstract:
A primer set for NAT2 diplotyping is selected from at least one of NAT2*4 primers, NAT2*5B primers, NAT2*6A primers, NAT2*7B primers, NAT2*12A primers, and NAT2*13A primers. The primer set is applied to Polymerase chain reaction (PCR) for NAT2- diplotyping analysis. The PCR results are then used to interpret acetylator phenotype for assessment the metabolism of arylamine-related drugs in patients.