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1. (WO2017151062) A METHOD OF DETERMINING A PRESENCE OF INTERACTION BETWEEN A SUBSTANCE MOLECULE AND A SUBSTRATE MOLECULE

Pub. No.:    WO/2017/151062    International Application No.:    PCT/SG2017/050101
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Sat Mar 04 00:59:59 CET 2017
IPC: G01Q 60/24
G01L 5/00
G01N 21/64
G01N 23/20
Applicants: NATIONAL UNIVERSITY OF SINGAPORE
Inventors: YAN, Jie
WINARDHI, Ricksen Surya
MINGXI, Yao
Title: A METHOD OF DETERMINING A PRESENCE OF INTERACTION BETWEEN A SUBSTANCE MOLECULE AND A SUBSTRATE MOLECULE
Abstract:
A method of determining a presence of interaction between a substance molecule and a stretched substrate molecule, the method comprising the steps of: providing the stretched substrate molecule, such that a first contact point of the stretched substrate molecule and a second contact point of the stretched substrate molecule are separated at a displacement; contacting the stretched substrate molecule with a solution, wherein the solution comprises the substance molecule or is suspected to comprise the substance molecule; and detecting a change in the displacement between the first contact point and the second contact point of the stretched substrate molecule, wherein the change in the displacement between the first contact point and the second contact point indicates the presence of interaction between the substance molecule and the stretched substrate molecule.